Edited by: Karen Young Kreeger
N. Funayama, F. Fagotto, P. McCrea, B.M. Gumbiner, "Embryonic axis induction by the armadillo repeat domain of b-catenin: Evidence for intracellular signaling," Journal of Cell Biology, 128:959-68, 1995. (Cited in more than 60 publications as of February 1997)
Comments by Barry Gumbiner, Memorial Sloan-Kettering Cancer Center
DOUBLE ROLE: Sloan-Kettering's Barry Gumbiner and colleagues found that beta-catenin plays a role in signal transduction, as well as cellular adhesion.
The lab of Barry Gumbiner at Memorial Sloan-Kettering Cancer Center in New York used frog embryos to look at how the process of adhesion contributes to development. To do this, they cloned beta-catenin cDNA, which...