T. Braun, M.A. Rudnicki, H.H. Arnold, R. Jaenisch, "Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death," Cell, 71:369-82, 1992.

M.A. Rudnicki, T. Braun, S. Hinuma, R. Jaenisch, "Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development," Cell, 71:383-90, 1992.

M.A. Rudnicki, P.N.J. Schnegelaberg, R.H. Stead, T. Braun, H.H. Arnold, R. Jaenisch, "MyoD or Myf-5 is required for the formation of skeletal muscle," Cell, 75:1351-9, 1993.

Michael A. Rudnicki (Institute for Molecular Biology and Biotechnology, McMaster University, Hamilton, Ontario, Canada): "Gene targeting has allowed the genetic dissection of the roles played by the myogenic regulatory factors (MRFs) in the development of skeletal muscle. The introduction of null [loss-of-function] mutations in Myf-5, MyoD, and myogenin into the germline of mice has revealed insights into the hierarchical relationships existing among...

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