L.A. Goldstein, D.F.H. Zhou, L.J. Picker, C.N. Minty, et al., "A human lymphocyte homing receptor, the Hermes antigen, is related to cartilage proteoglycan core and link proteins," Cell, 56, 1063-72, 24 March 1989.
Les Goldstein (Stanford University School of Medicine, Calif.): "This article, and the concurrent study by Ivan Stamenkovic, et al. (Cell, 56:1057, 1989), reported cloning of the lymphocyte homing receptor/adhesion molecule H-CAM(CD44), previously called the Hermes antigen. The cDNA revealed homology to cartilage link and proteoglycan core protein repeated domains, defining H-CAM(CD44) as a novel class of cell adhesion molecule (CAM) unrelated to previously described CAMs. Interest in the study stems in part from the role of H-CAM in lymphocyte homing via high endothelial venules, a critical determinant of immune responses. Immunologists have also been intrigued, however, by recent evidence that this molecule is involved in several other cell-cell interactions important in immune...
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