Image of the Day: Cellular Pulse

The protein RhoA coordinates pulses of movement in Caenorhabditis elegans cells.

Shawna Williams
Oct 29, 2018
A C. elegans cell during interphase as polarity is established (left). A two-cell embryo C. elegans shortly after cell division (right)

In a paper published October 1 in the Journal of Cell Biology, researchers led by Edwin Munro of the University of Chicago report that a protein known as RhoA is key to a process known as pulse contractility in C. elegans, which enables tissues to shape-shift during development.

J.B. Michaux et al., “Excitable RhoA dynamics drive pulsed contractions in the early C. elegans embryo,” J Cell Biol, doi:10.1083/jcb.201806161, 2018.