Image of the Day: Uncovered
Image of the Day: Uncovered

Image of the Day: Uncovered

Researchers discover cells in the early life stage of the Schistosoma mansoni parasite that contribute to adults’ reproductive systems.

Sukanya Charuchandra
Sukanya Charuchandra

Originally from Mumbai, Sukanya Charuchandra is a freelance science writer based out of wherever her travels take her. She holds master’s degrees in Science Journalism and Biotechnology. You can read...

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Jul 12, 2018

ABOVE: This image from confocal microscopy shows a snail with its shell removed that is infected with schistosome parasites.
BO WANG, STANFORD UNIVERSITY 

Classified as the deadliest neglected tropical disease by the World Health Organization, schistosomiasis is caused by blood parasites of the genus Schistosoma that travel from snails to water to humans. In research published in eLife on July 10, scientists identify five cells from the parasites’ early stage of infection that form adult stem cells, a portion of which contribute to the growth of the reproductive system. 

Parasite eggs that hatch in water bodies take up residence in snails, within which they reproduce in large numbers. These organisms come into contact with humans through contaminated water. In the course of infection, the schistosomes pierce human skin and develop into adults upon reaching the liver. The sole treatment available for the infection kills adult worms in humans. 

“The...

B. Wang et al., “Stem cell heterogeneity drives the parasitic life cycle of Schistosoma mansoni,” eLife, doi:10.7554/eLife.35449, 2018.

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