Menu

Image of the Day: Calcium Signaling

Researchers used light-sheet microscopy to form 3-D images of the process in primary cortical neurons from embryonic rats.

Feb 20, 2018
The Scientist Staff, The Scientist Staff

Calcium signaling in primary cortical neurons from embryonic rats imaged in 3-D with parallelized light-sheet microscopyK.M. DEAN ET AL.

To acquire an image of calcium signaling, Reto Fiolka, a cell biologist at the University of Texas Southwestern Medical Center, illuminated primary cortical neurons from embryonic rats with three separate light sheets using fluorescence microscopy. Each light sheet was detected independently, and they were combined to produce a 3-D image of calcium signaling. The novel technology allows the visualization of rapid microscopic events in three dimensions, and the researchers also used it to demonstrate other intracellular and biological processes. 

K.M. Dean et al., “Imaging subcellular dynamics with fast and light-efficient volumetrically parallelized microscopy,” Optica, doi:10.1364/OPTICA.4.000263, 2017.

April 2019

Will Car T Cells Smash Tumors?

New trials take the therapy beyond the blood

Marketplace

Sponsored Product Updates

Application of TruBIOME™ to Increase Mouse Model Reproducibility
Application of TruBIOME™ to Increase Mouse Model Reproducibility
With this application note from Taconic, learn about the effects of the microbiome on reproducibility and predictability and how TruBIOME™ helps researchers generate custom microbiota mouse models!
Getting More Consistent Results by Knowing the Quality of Your Protein
Getting More Consistent Results by Knowing the Quality of Your Protein
Download this guide from NanoTemper to learn how to identify and evaluate the quality of your protein samples!
Myth Busting: The Best Way to Use Pure Water in the Lab
Myth Busting: The Best Way to Use Pure Water in the Lab
Download this white paper from ELGA LabWater to learn about the role of pure water in the laboratory and the advantages of in-house water purification!
Shimadzu's New Nexera UHPLC Series with AI and IoT Enhancements Sets Industry Standard for Intelligence, Efficiency and Design
Shimadzu's New Nexera UHPLC Series with AI and IoT Enhancements Sets Industry Standard for Intelligence, Efficiency and Design
Shimadzu Corporation announces the release of the Nexera Ultra High-Performance Liquid Chromatograph series, incorporating artificial intelligence as Analytical Intelligence, allowing systems to detect and resolve issues automatically. The Nexera series makes lab management simple by integrating IoT and device networking, enabling users to easily review instrument status, optimize resource allocation, and achieve higher throughput.