Menu

Image of the Day: Cooking Up Neurons

Using different combinations of transcription factors, researchers create a diverse array of neurons from mouse skin cells.

May 11, 2018
The Scientist Staff, The Scientist Staff

Mouse neurons generated from a novel transcription-factor pair Neurog2/Brn2BALDWIN LAB/THE SCRIPPS RESEARCH INSTITUTE

On Wednesday (May 9), researchers reported in Nature that they created a “neuronal cookbook” of 76 transcriptional codes from which they can create different kinds of neurons from mouse fibroblast cells. The cells can mimic the characteristics of brain cells affected by neurological diseases, which may lead to screening for potential drugs to treat the disorders.

“The brain is incredibly complex, with thousands of different types of cells that are each involved in different diseases,” says study coauthor Kristin Baldwin, a neuroscientist at the Scripps Research Institute in La Jolla, California, in a statement. “The problem with understanding and treating the many disorders of the brain is that we cannot reproducibly produce the right types of brain cells. Now we have found more than 75 new ways to rapidly and reproducibly turn skin cells into neurons that we think will be much better representatives of different neurologic diseases than were previously available.”

R. Tsunemoto et al., “Diverse reprogramming codes for neuronal identity,” Nature, doi:10.1038/s41586-018-0103-5, 2018.

February 2019

Big Storms Brewing

Can forests weather more major hurricanes?

Marketplace

Sponsored Product Updates

Bio-Rad Showcases New Automation Features of its ZE5 Cell Analyzer at SLAS 2019
Bio-Rad Showcases New Automation Features of its ZE5 Cell Analyzer at SLAS 2019
Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb) today showcases new automation features of its ZE5 Cell Analyzer during the Society for Laboratory Automation and Screening 2019 International Conference and Exhibition (SLAS) in Washington, D.C., February 2–6. These capabilities enable the ZE5 to be used for high-throughput flow cytometry in biomarker discovery and phenotypic screening.
Andrew Alliance and Sartorius Collaborate to Provide Software-Connected Pipettes for Life Science Research
Andrew Alliance and Sartorius Collaborate to Provide Software-Connected Pipettes for Life Science Research
Researchers to benefit from an innovative software-connected pipetting system, bringing improved reproducibility and traceability of experiments to life-science laboratories.
Corning Life Sciences to Feature 3D Cell Culture Technologies at SLAS 2019
Corning Life Sciences to Feature 3D Cell Culture Technologies at SLAS 2019
Corning Incorporated (NYSE: GLW) will showcase advanced 3D cell culture technologies and workflow solutions for spheroids, organoids, tissue models, and applications including ADME/toxicology at the Society for Laboratory Automation and Screening (SLAS) conference, Feb. 2-6 in Washington, D.C.
Corning Introduces New 1536-well Spheroid Microplate
Corning Introduces New 1536-well Spheroid Microplate
High-throughput spheroid microplate benefits cancer research, drug screening