Two-photon calcium imaging demonstrates neurons firing in the cortex of a mouse brain. PORTERA-CAILIAU LAB/UCLAIn a mouse strain designed to model symptoms of autism, neurons don’t attenuate their firing following repeated whisker agitation. In normal mice, however, this neuronal activity eventually quiets down.
See C. X. He et al., “Tactile defensiveness and impaired adaptation of neuronal activity in the Fmr1 knockout mouse model of autism,” The Journal of Neuroscience, doi:10.1523/JNEUROSCI.0651-17.2017, 2017.
Interested in reading more?
The Scientist ARCHIVES
Become a Member of
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member?
