UNIVERSITY OF MICHIGANUsing human pluripotent stem cells and 3-D media, scientists have sparked the growth of an amniotic sac-like structure—“a hollow cyst, which contains a cavity (a lumen) that is enveloped by a layer of cells,” describes co-lead author Yue Shao in an email to The Scientist. They’ve dubbed it a post-implantation amniotic sac embryoid, PASE for short.
See Y. Shao et al., “A pluripotent stem cell-based model for post-implantation human amniotic sac development,” Nature Communications, 8:208, 2017.
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