Menu

Image of the Day: Goo for Growing Organoids

Scientists engineered a synthetic, nutrient-rich gel that feeds growing organoids as they mature from human pluripotent stem cells into 3-D bowels.

Oct 24, 2017
The Scientist Staff, The Scientist Staff

A mature intestinal organoid, grown from human pluripotent stem cells and a synthetic growth-promoting hydrogelMIGUEL QUIRÓS, UNIVERSITY OF MICHIGANTo cultivate organoids in culture, scientists bathe them in growth-promoting materials derived from mice. But this limits their use in treating human diseases due to the risk for zoonotic infections. To solve this problem, researchers engineered a synthetic gel that can also do the job.

See R. Cruz-Acuña et al., “Synthetic hydrogels for human intestinal organoid generation and colonic wound repair,” Nature Cell Biology, doi:10.1038/ncb3632, 2017.

Correction (October 27): The original credit for the image incorrectly listed a different coauthor. The Scientist regrets the error.

January 2019

Cannabis on Board

Research suggests ill effects of cannabinoids in the womb

Marketplace

Sponsored Product Updates

Cell culture made easy with new 24-channel pipetting heads for VIAFLO 96/384
Cell culture made easy with new 24-channel pipetting heads for VIAFLO 96/384
INTEGRA has responded to customers’ requests and developed two new 24-channel pipetting heads, extending the capabilities of its popular VIAFLO 96/384.
Horizon Discovery extends CRISPR Screening Service to primary human T cells
Horizon Discovery extends CRISPR Screening Service to primary human T cells
Horizon Discovery Group plc (LSE: HZD) (“Horizon” or “the Company”), a global leader in gene editing and gene modulation technologies, today announced the extension of its CRISPR Screening Service to includeex vivoT lymphocytes. The service extension meets the requirements of immunology-based research in drug discovery,enabling new gene targets to be identified in biologically and potentially therapeutically relevant settings.
pIC50: The Advantages of Thinking Logarithmically
pIC50: The Advantages of Thinking Logarithmically
Watch this webinar from Collaborative Drug Discovery to learn about how using pIC50 helps you get a better sense of the relative potencies, calculate the correct mean of multiple values, and select better sampling doses.
WIN a VIAFLO 96/384 to supercharge your microplate pipetting!
WIN a VIAFLO 96/384 to supercharge your microplate pipetting!
INTEGRA Biosciences is offering labs the chance to win a VIAFLO 96/384 pipette. Designed to simplify plate replication, plate reformatting or reservoir-to-plate transfers, the VIAFLO 96/384 allows labs without the space or budget for an expensive pipetting robot to increase the speed and throughput of routine tasks.