Scientists grew organoids that mimic human fetal brains and infected them with the Zika virus to model its neurological effects.
The Scientist Staff and The Scientist Staff
Brain organoid grown in culture, engineered from human induced pluripotent stem cells. Pictured are neural stem cells (blue, red) that propagate into neurons (green)UCLA BROAD STEM CELL RESEARCH CENTER, WATANABE ET AL., CELL REPORTS, 21:517-32, 2017. See M. Watanabe et al., “Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection,” Cell Reports, 21:517-32, 2017.
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