Mouse gut epithelium is stained red. In the intestinal lumen, Mucispirillum is stained green, Salmonella is stained pink, and other bacteria are stained blue.
B. STECHER/LMU MUNICH
Researchers report the bacterial species Mucispirillum schaedleri provides some protection against Salmonella infection in mice. Salmonella and Mucispirillum compete directly for resources in the gut, and Mucispirillum is able to limit the spread of Salmonella infection and its virulence, write the authors of a recent study.
S. Herp et al., “Mucispirillum schaedleri antagonizes Salmonella virulence to protect mice against colitis,” Cell Host Microbe, doi:10.1016/j.chom.2019.03.004, 2019.
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