Image of the Day: Mouse Cornea

Researchers discover a genetic link in mice between thinner corneas and an increased risk of developing glaucoma.

The Scientist Staff and The Scientist Staff
Jan 30, 2018

Sections of mouse corneas stained for POU6F2 (A), with arrow pointing to developing cornea and corneal epithelium, and arrowheads noting neuroblasts destined to become retinal ganglion cells; and control, with primary antibody for POU6F2 omitted (B)REBECCA KING AND COLLEAGUES

The best-known risk factor for developing glaucoma is having a thin cornea. Researchers have identified a transcription factor, POU6F2, that appears to help regulate corneal development in mice. They hope it may one day aid in early detection of glaucoma.

R. King et al., “Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma,” PLOS Genet, doi:10.1371/journal.pgen.1007145, 2018.

Correction (April 11, 2019): The reference originally had the title of another paper. The article has been corrected to include the correct study title. The Scientist regrets the error.