Image of the Day: Multicolor Brain

A newly developed imaging technology visualizes entire mouse brains in two and three dimensions using multicolor fluorescence microscopy.

Chia-Yi Hou
Apr 22, 2019
Dive into a mouse brain whose cells have been labeled using chromatic multiphoton serial (ChroMS) microscopy.

Researchers describe a new technique for imaging whole mouse brains, called chromatic multiphoton serial (ChroMS) microscopy, in Nature Communications on April 10. Their method uses different wavelengths to show distinct proteins in various colors. 

L. Abdeladim et al., “Multicolor multiscale brain imaging with chromatic multiphoton serial microscopy,” Nature Communications, doi:10.1038/s41467-019-09552-9, 2019.