Image of the Day: Unseen Trauma

Pressure from simulated blast waves, similar to those generated by explosives, induced molecular markers of stress and injury within mouse retinas.

The Scientist Staff
Jun 20, 2017
Immunofluorescent image of a retina from a mouse subjected to blast wave pressure. Glial fibrillary acidic proteins (green), indicating glial cell activation, and pathology-associated phosphorylated tau (red) are coexpressed in glial cells (yellow).
    "Our results may explain symptoms of visual dysfunction reported by combat veterans who have experienced [traumatic brain injury]," says senior author Heather West Greenlee of Iowa State University College of Veterinary Medicine in a news release.
See N. Mammadova et al., “Lasting retinal injury in a mouse model of blast-induced trauma,” American Journal of Pathology, doi:10.1016/j.ajpath.2017.03.005, 2017.