A new genetic sensor called PRISM makes use of a host cell’s DNA replication machinery to trigger fluorescence in neurons with damaged DNA.

Maligned peptides such as the Alzheimer’s-associated amyloid precursor protein may have critical roles in the healthy brain.

When the bacterium Caulobacter crescentus runs low on fuel, it can still replicate by clustering its remaining ATP around the cell division enzyme DivJ.

Extinction is a natural part of life on Earth. But occasionally, extinction rates have surged far beyond usual levels, driving mass extinction events that have reshaped the trajectory of life.

Genetic studies have made it clear that eukaryotic horizontal gene transfer can and does happen. Exactly how, though, remains speculative.

A new technique goes beyond CRISPR and writes two complementary strands of DNA directly into the genome.

How scientists aim to induce an immune response against addictive drugs

Advances in genetics in recent years has revealed that many apparently exclusive pairs in fact sometimes mate with individuals other than their partner, but social monogamy is widespread.

A visual guide to streamlining high-plex, high-throughput workflows

Known as SLiMs, these stretches of up to 10 amino acids play notable roles in cell biology, including responses to viral invasion.

Nanoparticle-coated bacteria carry cancer-derived proteins to dendritic cells, enabling the immune system to launch a response in a mouse model.

Diverse lines of evidence point to humans’ presence in the New World long before the dawn of Clovis culture. But rewriting this chapter of human history raises many questions about how these early people came to inhabit these continents.

Scientists have pinpointed several pathways through which the immune system could disrupt neuronal functioning and thereby lead to psychotic symptoms.

A new methodology combines existing techniques to reveal the specific function and location of multiple types of neurons at once.

Some studies suggest that associations between the health of children and the experiences of their parents or grandparents may be due to epigenetic mechanisms, but confounding factors challenge this interpretation.

Researchers can now explain how some marine plants obtain their nitrogen.

From diagnosis to tracking treatment responses, bacteria and other microbes in the blood, gut, and tumors of cancer patients may provide helpful hints for improving their care.

When micronuclei rupture, chromosomes break, recombine, and form circles, causing inflammation and promoting carcinogenic growth.

Scientists have documented examples of corals “remembering” prior exposure to heat stress in the field, and are now simulating these phenomena in the lab to better understand their cellular and molecular underpinnings.