Illustration of the cerebellum
Infographic: The Cerebellum’s Many Roles Beyond Motor Control
Researchers have discovered that the small structure is involved language, emotion, and may other high-order brain processes.
Infographic: The Cerebellum’s Many Roles Beyond Motor Control
Infographic: The Cerebellum’s Many Roles Beyond Motor Control

Researchers have discovered that the small structure is involved language, emotion, and may other high-order brain processes.

Researchers have discovered that the small structure is involved language, emotion, and may other high-order brain processes.

ABOVE: © julia moore, mooreillustrations.com
Infographics
To flag neurons that have experienced genotoxic stress, researchers developed an in vivo sensor using an adeno-associated viral vector, called PRISM. Because a cell’s DNA damage response (DDR)—which activates in response to stressors such as environmental toxins or the buildup of misfolded proteins—also responds to invading pathogens, PRISM has an easier time transfecting cells whose damage response mechanisms are preoccupied with existing DNA damage. Once inside, the virus hijacks the neuron’s DNA replication machinery, which reverts an engineered frameshift mutation in the virus and thereby prompts the production of a fluorescent protein that can be observed via microscopy.
Infographic: DNA Damage Viewed with Unprecedented Clarity
Amanda Heidt | Aug 15, 2022
A new genetic sensor called PRISM makes use of a host cell’s DNA replication machinery to trigger fluorescence in neurons with damaged DNA.
Infographic showing how neurodegenerative diseases have long been associated with aggregations of apparently toxic proteins
Infographic: Secret Lives of Neurodegeneration-Linked Proteins
Catherine Offord | Aug 1, 2022
Maligned peptides such as the Alzheimer’s-associated amyloid precursor protein may have critical roles in the healthy brain.
Caulobacter crescentus, concentrating DivJ
Infographic: Nutrient Scarcity Drives Phase Separation in Bacteria
Viviane Callier | Jul 18, 2022
When the bacterium Caulobacter crescentus runs low on fuel, it can still replicate by clustering its remaining ATP around the cell division enzyme DivJ.
Illustration of creatures from today’s crisis
Infographic: A Look at the Big Five Mass Extinctions
Katarina Zimmer | Jul 18, 2022
Extinction is a natural part of life on Earth. But occasionally, extinction rates have surged far beyond usual levels, driving mass extinction events that have reshaped the trajectory of life.
Illustration of a DNA virus sneaking genetic material into a host’s nucleus
Infographic: Possible Mechanisms of Gene Transfer in Eukaryotes
Christie Wilcox | Jul 5, 2022
Genetic studies have made it clear that eukaryotic horizontal gene transfer can and does happen. Exactly how, though, remains speculative.
Two prime editing guide RNAs (pegRNAs), deliver Cas9 enzymes to targeted regions of the genome.
Infographic: Two Guide RNAs Make for Large, Stable Insertions
Dan Robitzski | Jun 13, 2022
A new technique goes beyond CRISPR and writes two complementary strands of DNA directly into the genome.
Vaccine illustration 
Infographic: Inducing Active Immunity Against Opioid Overdose
Tori Rodriguez | Jun 13, 2022
How scientists aim to induce an immune response against addictive drugs
Infographic showing genetic and social monogamy in birds
Infographic: A New Look at Monogamy Across the Animal Kingdom
Catherine Offord | Jun 1, 2022
Advances in genetics in recent years has revealed that many apparently exclusive pairs in fact sometimes mate with individuals other than their partner, but social monogamy is widespread.
iStock
Simplifying Spatial and Molecular Profiling with End-to-End Services
Canopy Biosciences | May 20, 2022
A visual guide to streamlining high-plex, high-throughput workflows
Infographic about SLiMs in SARS-CoV-2 Infection
Infographic: Short Protein Motifs’ Role in SARS-CoV-2 Infection
Conchita Fraguas Bringas , Jakob Nilsson | May 16, 2022
Known as SLiMs, these stretches of up to 10 amino acids play notable roles in cell biology, including responses to viral invasion.
Illustration showing how following radiation therapy, which triggers the release of cancer-specific antigens, researchers injected Salmonella typhimurium bacteria covered in positively charged nano- particles near tumors in mice.
Infographic: Salmonella Shuttle Tumor Antigens to Immune Cells
Dan Robitzski | May 16, 2022
Nanoparticle-coated bacteria carry cancer-derived proteins to dendritic cells, enabling the immune system to launch a response in a mouse model.
Illustrated map showing where evidence was found of the earliest humans
Infographic: Mixed Evidence on Human Occupation of the Americas
Emma Yasinski | May 2, 2022
Diverse lines of evidence point to humans’ presence in the New World long before the dawn of Clovis culture. But rewriting this chapter of human history raises many questions about how these early people came to inhabit these continents.
Illustration comparing neural pathway and the humoral pathway
Infographic: How the Body’s Defenses Attack the Brain
Diana Kwon | Apr 18, 2022
Scientists have pinpointed several pathways through which the immune system could disrupt neuronal functioning and thereby lead to psychotic symptoms.
Illustration showing how calcium imaging and HCR-FISH combined is a technique called comprehensive readout of activity and cell type markers (CRACK)
Infographic: Simultaneously Studying Neuron Structure and Function
Dan Robitzski | Apr 18, 2022
A new methodology combines existing techniques to reveal the specific function and location of multiple types of neurons at once.
Illustration showing epigenetic changes
Infographic: Questions Linger About Epigenetic Inheritance
Catherine Offord | Apr 4, 2022
Some studies suggest that associations between the health of children and the experiences of their parents or grandparents may be due to epigenetic mechanisms, but confounding factors challenge this interpretation.
Infographic showing how a new bacteria species called <em>Candidatus Celerinatantimonas neptuna</em> lives in seagrass and how it provides the plant with nitrogen
Infographic: Nitrogen-Fixing Bacteria Live Inside Seagrass Roots
Rachael Moeller Gorman | Mar 14, 2022
Researchers can now explain how some marine plants obtain their nitrogen.
Illustration showing microbial signatures of cancer in the body
Infographic: Putting Cancer’s Unique Microbiomes to Use
Jef Akst | Mar 14, 2022
From diagnosis to tracking treatment responses, bacteria and other microbes in the blood, gut, and tumors of cancer patients may provide helpful hints for improving their care.
Infographic showing how bursting micronuclei promote cancer
Infographic: Chromosome Errors Cause Micronuclei and Drive Cancer
Samuel F. Bakhoum | Mar 1, 2022
When micronuclei rupture, chromosomes break, recombine, and form circles, causing inflammation and promoting carcinogenic growth.
Illustration showing coral health outcomes in response to bleaching events
Infographic: How Corals Remember the Past, Prepare for the Future
Amanda Heidt | Feb 14, 2022
Scientists have documented examples of corals “remembering” prior exposure to heat stress in the field, and are now simulating these phenomena in the lab to better understand their cellular and molecular underpinnings.