Infographic: Effects of Satellite DNA–Binding Proteins
The linkers gather chromosomes together into chromocenters.
Oct 1, 2018
Sukanya Charuchandra
In cells with normal satellite DNA–binding proteins, chromocenters pull several chromosomes together.

© lucy reading-ikkanda
When the function of the DNA-binding proteins is experimentally altered, chromocenter formation also changes.

© lucy reading-ikkanda
Elimination of satellite DNA–binding proteins | Overexpression of satellite DNA–binding proteins | Protein binding to abnormal sites |
Chromocenters cannot form; chromosomes bleb away from the nucleus in micronuclei | Chromosomes gather in larger bunches than normal, limiting the number of chromocenters formed | All regions in contact with the DNA-binding proteins are pulled into chromocenters |
Read the full story.