The third generation of glutamate sensors, iGluSnFR3, tracks glutamate release at the synapse level.1 Upon binding to glutamate, the reporter changes its conformation, intensifying the signal of its fluorescent protein.
- Aggarwal A, et al. Glutamate indicators with improved activation kinetics and localization for imaging synaptic transmission. Nat Methods. 2023;20(6):925-934.
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