Messing with HIV

Sangamo Biosciences is putting a different spin on gene therapy. 

Jef Akst
Jef Akst

Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf...

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Jun 1, 2012

Infographic: Messing with HIV
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LUCY READING-IKKANDA

Sangamo Biosciences is putting a different spin on gene therapy. Rather than replace or supplement a mutated gene with an accurate copy, Sangamo researchers are introducing a mutant copy of the gene for the HIV co-receptor CCR5 into the T cells of HIV patients. This prevents the expression of CCR5 on the cell’s surface, and thus inhibits HIV from infecting cells.

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