Mouthwash vs. Whole Blood

Mouthwash vs. Whole Blood In your article on DNA extraction from mouthwash,1 you stated that this is a new procedure and it can be used as an alternative for DNA extractions from whole blood. We have been using this procedure for a few years now, so it's not really that new. And it cannot be used as an alternative for DNA extractions from whole blood all the time; only in special cases. The quality and quantity of DNA extracted from a mouthwash sample is much smaller and less than that from

Golnush Sharafsaleh
Nov 24, 2002

Mouthwash vs. Whole Blood

In your article on DNA extraction from mouthwash,1 you stated that this is a new procedure and it can be used as an alternative for DNA extractions from whole blood. We have been using this procedure for a few years now, so it's not really that new. And it cannot be used as an alternative for DNA extractions from whole blood all the time; only in special cases. The quality and quantity of DNA extracted from a mouthwash sample is much smaller and less than that from whole blood. Sure, this is a good technique to use when a child doesn't want to get poked, or if an adult acting like a child gives you a hard time, or when you just have no other option, but the best DNA quality comes from whole blood--unless you transform cell lines first and then extract DNA from...