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wrinkled hands held over blue water
Why Do Fingers Prune?
After a long soak in the tub, fingers emerge looking like raisins. The real reason for this curious phenomenon lies under the skin.
Why Do Fingers Prune?
Why Do Fingers Prune?

After a long soak in the tub, fingers emerge looking like raisins. The real reason for this curious phenomenon lies under the skin.

After a long soak in the tub, fingers emerge looking like raisins. The real reason for this curious phenomenon lies under the skin.

Magazine Issue

Orange bacteria on a green and orange background.
Bacterial Time Capsules May Inform Future Medicines
Danielle Gerhard, PhD | Nov 1, 2023 | 2 min read
Historical samples of bloodstream infections hold secrets to Escherichia coli’s evolutionary history and the emergence of virulent clones.
3d illustration of microscopic close up showing viruses and intestine villus into digestive tract.
The Viral Microbiome
Ida Emilie Steinmark, PhD | Nov 1, 2023 | 2 min read
Humans harbor both bacteria and viruses that help keep us healthy. Soon, they might cure us too.
A dark haired man is asleep on a grey couch under a darker grey blanket. A box of tissues is under his arm, and he is holding a tissue in one hand.
Why Do I Sleep So Much When I Am Sick?
Shelby Bradford, PhD | Nov 1, 2023 | 2 min read
Some elements of human immune systems serve important functions beyond fighting infections.
A female scientist holds up a burning funnel.
A Ticking Firebomb
Laura Tran, PhD | Nov 1, 2023 | 2 min read
Annalise Rogalsky finally got the potassium metal to react, but not during her experiment.
Image of cochlear implant and hearing aid.
Reversing Hearing Loss
Laura Tran, PhD | Nov 1, 2023 | 2 min read
Gene reactivation restored hearing after loss in mice, but the timing of intervention is key.
Back view of people clapping for a person standing in the front.
In Fall, Scientists Rise High
Meenakshi Prabhune, PhD | Nov 1, 2023 | 2 min read
Science awards remind us that seemingly overnight success takes years of hard work and patience.
Human lung with viruses
Gut Signals Influence Lung Responses to Infection
Mariella Bodemeier Loayza Careaga, PhD | Nov 1, 2023 | 2 min read
Diet-derived molecules spur a biological mechanism in the lung barriers of mice that prevents viral lung injury.
Genome sequence map concept
Mind the Genome Gap
Mariella Bodemeier Loayza Careaga, PhD | Nov 1, 2023 | 2 min read
Population geneticist Tábita Hünemeier seeks out isolated indigenous groups living in the Brazilian Amazon rainforest to expand understanding of the human genome.
Orange bacteria on a green and orange background.
Science Crossword Puzzle
Stella Zawistowski | Nov 1, 2023 | 1 min read
Put on your thinking cap, and take on this fun challenge.
Icon representing detection mode
Improving Microplate Reader Measurements
BMG LABTECH | Nov 1, 2023 | 2 min read
Researchers can choose their own microplate adventure with these critical considerations for application setup.
Orange rod-shaped bacteria over a red and purple background.
Macrophages Curtail Tuberculosis
Danielle Gerhard, PhD | Nov 1, 2023 | 2 min read
Two autophagy genes work together to stop Mycobacterium tuberculosis dead in its tracks.
Conceptual blue wireframe image of human body with illuminated points and DNA helix overlay.
Unraveling the Mystery of Zombie Genes
Iris Kulbatski, PhD | Oct 31, 2023 | 6 min read
Digging into how and why some genes are resurrected after death sounds morbid, but it has practical applications. 
Diagram tracking changes in gene expression
Ticker Tape Technology Records Cell History
Danielle Gerhard, PhD | Oct 2, 2023 | 1 min read
Researchers developed a novel protein fiber that tracks transcriptional events over time in living cells. This could shine a light on gene regulation during development or after cellular perturbations.
Illustration of virus with needle puncturing membrane
Designer Peptoids Pop Viral Membranes
Laura Tran, PhD | Oct 2, 2023 | 2 min read
Bioinspired small molecules combat viral threats by targeting a common feature in enveloped viruses, making them useful against a wide range of viruses.
Fluorescently labeled neuron cell bodies in blue in the center compartment of a three-compartment microfluidic chamber grow through tiny grooves to enter the left and the right chambers, where they extend axons fibers, also shown in blue.
Visualizing Axon Pruning
Tiffany Garbutt, PhD | Oct 2, 2023 | 2 min read
During development, neurons trim hundreds of excess axons in an intricately coordinated destructive process.
Lipid nanoparticle
Which Gene Therapy Delivery Vector Will Emerge Victorious? 
Danielle Gerhard, PhD | Oct 2, 2023 | 2 min read
In the race to deliver successful gene therapies, frontrunner AAVs come head to head with underdog lipid nanoparticles. 
An illustration of a dividing cancer cell.
Striking a Balance for Perfect Images
The Scientist Staff | Oct 2, 2023 | 2 min read
Advanced microscope systems enable researchers to perform high-resolution live-cell imaging, while maintaining cellular health.
Machine Learning Seamless Pattern
A Big Data Approach to Life Science
Mariella Bodemeier Loayza Careaga, PhD | Oct 2, 2023 | 2 min read
As a group leader at the Broad Institute, Shantanu Singh develops tools to tackle high-dimensional biological data.
Lipofuscin autofluorescence was quenched using TrueBlack®, allowing effective visualization of glial cells (GFAP antibody stain, cyan) and cell nuclei (magenta) in human cerebral cortex cryosections.
Stepping Out of the Background
The Scientist Staff | Oct 2, 2023 | 1 min read
New innovations for reducing nonspecific fluorescence offer researchers clearer pictures and more multiplexing possibilities.
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