NGS library preparation involves repeated liquid transfers alongside steps that require careful control of volumes, temperature, and sample handling. As more samples move through a workflow, normalization, PCR cleanup, and size selection can add considerable hands-on work and opportunities for variability.
Automation can be introduced at individual steps or across a more complete library-preparation workflow. This compendium brings together three application notes examining automated approaches to the complete library preparation process. The resources provide step-by-step protocols alongside performance data to help researchers consider where automation may have the greatest impact on their workflows.
Download this compendium to
- Identify NGS library prep stages that may benefit most from automation
- Compare automation requirements across size selection, cleanup, and normalization
- Examine how bead handling and adjustable size-selection ratios affect workflow design
- Consider how throughput, reaction conditions, and sample-specific volumes shape automation needs
