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Lee Hartwell won the 2001 Nobel Prize in Medicine or Physiology for his pioneering work characterizing yeast cell-cycle mutants. He now directs the Fred Hutchinson Cancer Research Center, and has been a driving force in organizing a program to uncover cancer biomarkers. His vision for how this will play out appears on page 18.

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When Jeremy L. Peirce, began studying molecular biology, his gel documentation system consisted of "the old Polaroid instant film." Such systems have come a long way, as Peirce learned in his review of more than two dozen on page 28. Today, Peirce is a postdoctoral researcher studying the genetics of complex traits at the University of Tennessee Health Science Center.

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San Francisco-based Monya Baker has contributed to Wired, The Economist, New Scientist, and Nature Biotechnology. On page 14 she writes about the challenges faced in creating...

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