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Cold Spring Harbor Laboratory bioinformatics professor Lincoln Stein was in graduate school when he was bitten by the programming bug. Tasked with the job of assembling cDNA sequences, the young MD/PhD student refused to pay the weekly fee Harvard charged to use their programs. "So I learned assembly language, because that was the only language available," and he wrote it himself. Today Stein is more partial to Perl. He writes about the evolution of bioinformatics on page 31.

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As a Marine Biology Laboratory fellow in 2004, Karen Heyman got a healthy dose of neuroscience, studying neural systems and behavior. More recently, when researchers at UCLA generously let her sit in on their journal club, she started learning about long-term potentiation, about which she writes on page 14. She found the science fascinating, but the competition within the controversial field was at least as intriguing.

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