Microbiome Influences

Researchers find that gender, education level, and breastfeeding can affect humans’ commensal microbial communities.

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WIKIMEDIA, MATTOSAURUSThe human microbiome is essential to health, and its disruption can lead to disease. Now, using data from the Human Microbiome Project (HMP), which has sampled the microbial communities of 300 healthy people at 18 body sites and analyzed additional samples from the same individuals, Patrick Schloss and Tao Ding of the University of Michigan have found that specific life-history events—namely, gender, education, and whether a person was breastfed as an infant—affected the composition of the body’s microbiomes as an adult. They published their results last week (April 16) in Nature.

“If a certain community of bacteria is associated with a specific life history trait, it is not such a stretch to imagine that there may be microbiome communities associated with illnesses such as cancer,” Schloss told The Conversation. Of course, he added, such correlations do not necessarily point to the cause of the microbiome differences between individuals. “We really don’t have a good idea for what determines the type of community you’ll have at any given body site.”

Level of education, for example, could affect the microbial makeup of the vagina as a result of other factors, such as wealth and social status. “I think that it is impossible to tease out the individual effects of education, sexual behavior, vaginal hygiene behavior, ethnicity, and social ...

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Meet the Author

  • Jef Akst

    Jef Akst was managing editor of The Scientist, where she started as an intern in 2009 after receiving a master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses.
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