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Cellular therapy. 3d illustration
Expert JeWell-ry Designers
Analyzing organoids has proven slow and cumbersome for scientists. But a new technique may speed things up, producing 3D images of hundreds of organoids per hour.
Expert JeWell-ry Designers
Expert JeWell-ry Designers

Analyzing organoids has proven slow and cumbersome for scientists. But a new technique may speed things up, producing 3D images of hundreds of organoids per hour.

Analyzing organoids has proven slow and cumbersome for scientists. But a new technique may speed things up, producing 3D images of hundreds of organoids per hour.

Modus Operandi
Broken DNA
DNA Damage Viewed with Unprecedented Clarity
Amanda Heidt | Aug 15, 2022 | 3 min read
A new tool called PRISM draws on virus-host interactions and a DNA repair pathway to help researchers visualize how cellular stress may contribute to neurodegenerative disease.
Genetic Syndrome and Genetic Disorder, 3D illustration of science concept.
With Two RNA Guides, Editing Technique Writes Long DNA Insertions
Dan Robitzski | Jun 13, 2022 | 4 min read
The approach, called GRAND, uses a second guide RNA to write complementary strands of DNA in targeted genomic locations, resulting in efficient insertions that can be hundreds of base pairs long.
Conceptual image of blue neurons with glowing segments over blue background.
CRACK Method Reveals Novel Neuron Type in Mouse Brain
Dan Robitzski | Apr 18, 2022 | 4 min read
A new technique reveals cells’ precise locations and functions in the brain. Its developers have already used it to identify a previously unknown neuron type.
An illustration depicting pores on a membrane
DNA Nanopore Sequencing Adapted for Protein Sequence Comparisons
Sophie Fessl | Feb 14, 2022 | 4 min read
Researchers link a stretch of DNA to a peptide of interest and measure current changes as the molecule is pulled by a helicase through a nanopore.
Abstract graphene structures
Synthetic Organelles Let Researchers Control Cell Behavior
Catherine Offord | Nov 1, 2021 | 3 min read
A technique that reversibly bundles tagged cargo into artificial membraneless compartments gives scientists the ability to switch cell processes on and off.
Saccharomyces cerevisiae yeast, 3D illustration. Microscopic fungi, baker's or brewer's yeast, are used as probiotics to restore normal flora of intestine
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Amanda Heidt | Sep 1, 2021 | 3 min read
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
corals in water with fish
First Immortal Cell Line Cultured for Reef-Building Corals
Amanda Heidt | Jul 1, 2021 | 3 min read
Lab-grown cells from the reef-building coral Acropora tenuis provide new opportunities to study bleaching, symbioses, and biomineralization.
liquid-containing tube labeled Laboratory Test Wastewater Sample SARS-CoV-2
Sewage Sampling Robots Speed SARS-CoV-2 Detection
Ruth Williams | May 1, 2021 | 3 min read
An automated wastewater monitoring technique could enable researchers to predict outbreaks of the virus up to a week in advance.
Infographic: Light Triggers Photocage Opening, Apoptosis Inhibition
Jef Akst | Jan 1, 2021 | 1 min read
Researchers develop a caspase inhibitor that only works after being irradiated with UV light, giving them control over apoptosis in human cells.
Light-Activated Molecules Stop Apoptosis at the Flip of a Switch
Jef Akst | Jan 1, 2021 | 3 min read
A new inhibitor gives researchers the ability to control programmed cell death in cultured human T cells.
Bacterial Superglue Enables Antiviral Antibody Discovery
Ruth Williams | Jul 13, 2020 | 3 min read
Testing out combinations of antiviral proteins from llamas could help researchers create potent virus-neutralizing multimers.
Vaccines Without Vials, Fridges, or Needles
Ruth Williams | Jun 1, 2020 | 3 min read
A novel preparation technique could facilitate vaccine preservation, transportation, and administration.
Wrist-Mounted Air Pollution Detector
Claire Jarvis | May 1, 2020 | 3 min read
A novel sampler records data on a broad range of environmental contaminants.
Precision Membrane Puncture Enables Efficient Cell Transfection
Ruth Williams | Apr 1, 2020 | 3 min read
A device for piercing individual holes in cell membranes allows vector-free DNA delivery while maintaining cell viability.
Gene Editing Reaches Plant Mitochondria
Ruth Williams | Mar 1, 2020 | 3 min read
Modified gene editing machinery enables targeted disruptions of mitochondrial genes in rice and rapeseed plants.
an illustration of bacteria
Genome Data Enable Capture of Elusive Microbes
Ruth Williams | Jan 13, 2020 | 3 min read
Using reverse genetics, researchers create antibodies to reel in previously uncultured bacteria.
CRISPR-Based Tool Expands DNA-Hydrogel Versatility
Ruth Williams | Dec 1, 2019 | 3 min read
DNA-responsive polymer gels used for releasing drugs, encapsulating cells, and much more now have greater adaptability thanks to the Cas12a nuclease.
Streamlined Artificial Chromosome Creation
Ruth Williams | Nov 1, 2019 | 3 min read
Recruiting an epigenetic instigator of centromere formation into large segments of cloned DNA facilitates their transformation into artificial chromosomes.
Remote Control of Peripheral Nerves
Ruth Williams | Oct 1, 2019 | 3 min read
An implantable wireless device with microfluidic and optical components allows manipulation of individual nerve fibers in mice’s extremities.
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