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Massively Parallel Perturbations
Ruth Williams | Mar 1, 2017
Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.
Deep Pocket Exploration
Ruth Williams | Feb 1, 2017
A modification to traditional docking software enables the examination of a ligand’s passage into its receptor.
New Technique Enables Observation of Accessible Chromatin
Ruth Williams | Jan 1, 2017
A test tube-based genome-labeling technique has been brought under the microscope.
Ruth Williams | Dec 1, 2016
Engineered circuits detect endogenous transcription factors to drive cellular outputs.
Neural Connectome Method Uses mRNA Barcodes
Ruth Williams | Nov 1, 2016
Researchers swap microscopy for RNA sequencing to track neural paths in the mouse brain.
How to Track Translation in Living Cells
Ruth Williams | Oct 1, 2016
Four independent research groups develop techniques for visualizing peptide production in living cells.
Promoting Protein Partnerships
Ruth Williams | Sep 1, 2016
Scientists generate new protein-protein interactions at an impressive PACE.
Wanted: Transcriptional Regulators
Ruth Williams | Aug 1, 2016
Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.
A New Way to ID Targets of RNA-Binding Proteins
Ruth Williams | Jul 1, 2016
The catalytic domain of an RNA-editing enzyme is fused with RNA-binding proteins.
Gut Bacteria for Insect RNAi
Ruth Williams | Jun 1, 2016
Lacing insect food with microbes encoding double-stranded RNAs can suppress insect gene expression.