Modus Operandi
Massively Parallel Perturbations
Massively Parallel Perturbations
Ruth Williams | Mar 1, 2017
Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.
Deep Pocket Exploration
Deep Pocket Exploration
Ruth Williams | Feb 1, 2017
A modification to traditional docking software enables the examination of a ligand’s passage into its receptor.
New Technique Enables Observation of Accessible Chromatin
New Technique Enables Observation of Accessible Chromatin
Ruth Williams | Jan 1, 2017
A test tube-based genome-labeling technique has been brought under the microscope.
Synthetic Sensors
Synthetic Sensors
Ruth Williams | Dec 1, 2016
Engineered circuits detect endogenous transcription factors to drive cellular outputs.
Neural Connectome Method Uses mRNA Barcodes
Neural Connectome Method Uses mRNA Barcodes
Ruth Williams | Nov 1, 2016
Researchers swap microscopy for RNA sequencing to track neural paths in the mouse brain.
 
How to Track Translation in Living Cells
How to Track Translation in Living Cells
Ruth Williams | Oct 1, 2016
Four independent research groups develop techniques for visualizing peptide production in living cells.
Promoting Protein Partnerships
Promoting Protein Partnerships
Ruth Williams | Sep 1, 2016
Scientists generate new protein-protein interactions at an impressive PACE.
Wanted: Transcriptional Regulators
Wanted: Transcriptional Regulators
Ruth Williams | Aug 1, 2016
Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.
A New Way to ID Targets of RNA-Binding Proteins
A New Way to ID Targets of RNA-Binding Proteins
Ruth Williams | Jul 1, 2016
The catalytic domain of an RNA-editing enzyme is fused with RNA-binding proteins.
Gut Bacteria for Insect RNAi
Gut Bacteria for Insect RNAi
Ruth Williams | Jun 1, 2016
Lacing insect food with microbes encoding double-stranded RNAs can suppress insect gene expression.