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Article

Monitoring Cell Culture Media Quality Over Time

A fluorescence-based method for tracking media degradation across different storage conditions

Brought to you byHORIBA

Cell culture media can degrade during storage, altering the components required for consistent cell growth, yield, and quality. To protect their cultures, researchers need a reliable technique for analyzing media composition. 

A-TEEM™ spectroscopy paired with principal component analysis provides a rapid method to identify and evaluate media quality. This application note shows how A-TEEM™ molecular fingerprinting can classify cell culture media types and assess them under cold and ambient storage conditions. Together, these results can help researchers confirm media quality before it becomes an uncontrolled variable.

Download this application note to

  • Compare molecular fingerprints across DMEM, RPMI, Ham’s F, and CHO culture media
  • Assess potential media degradation in samples stored at 4°C or exposed to ambient temperature and light
  • Consider how these techniques can inform supplementation and replenishment decisions in biomanufacturing

Sponsored by

  • Horiba Instruments

Top Image Credit:

©iStock, anamejia18

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