Neuroscience

Cognitive neuroscientists explore the dynamics of mental fatigue and self-control.

Genetics and tolerance shake up how alcohol affects each person, creating a unique cocktail of experiences.

Studies shed light on pain perception, placebo effect pathways, and how human stem cells can be used to model pain. 

Ke Hou generated a compound that prevents tau aggregation in the murine brain, but the potential Alzheimer’s disease therapy also had a surprising property.

Experts from the Women’s Brain Foundation and bit.bio will explore the importance of sex-specific in vitro models for neurological research and drug discovery.

Patterns of human endogenous retrovirus expression linked to decreased neurodegenerative disease risk.

Researchers mimic the antianxiety effects of psychedelics by identifying and activating specific brain regions in an important step towards developing therapeutics that do not cause hallucinations.

A brain-derived hormone that improves bone health could guide new treatments for age-related bone conditions. 

Human brain and blood vessel organoids merged to form blood-brain barrier assembloids could provide clues into neurological diseases.

Depending on the “clamped” parameter, patch clamp configurations probe different aspects of a cell's electrical activity.

Placebo analgesia might be all in the head, but that doesn’t mean it’s not real.

Transcriptomic studies of the shrew’s remarkably plastic brain could provide new insights into neurodegenerative diseases.

Scientists use innovative stem cell culture models to progress retinal cell therapy research.

In mice, dampening the activity of area postrema neurons diminished cancer-induced muscle and fat loss and increased lifespan.

Scientists identified the mechanoreceptor that triggers the distinctive shake-off behavior observed in mice when they become wet.

Nematodes can sniff out trouble, kicking off a mitochondrial defense in the gut to fend off bacterial invaders.

Dysfunctional neurons in the cerebellum, a brain region that controls motor functions, reduced REM sleep in mice.

Agnès Lacreuse investigates cognitive aging and women’s health in nonhuman primates.

Cellular oxygen consumption in the brain may shed new light on Alzheimer’s disease onset, progression, and treatment.