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Conceptual 3D rendering of human body consisting of grey strings on blue background.
Ancient Alleles Shed Light on Atherosclerosis Risk
Calculating the polygenic risk scores of ancient humans such as Ötzi the iceman helps researchers understand the genetic predisposition to cardiovascular disease.
Ancient Alleles Shed Light on Atherosclerosis Risk
Ancient Alleles Shed Light on Atherosclerosis Risk

Calculating the polygenic risk scores of ancient humans such as Ötzi the iceman helps researchers understand the genetic predisposition to cardiovascular disease.

Calculating the polygenic risk scores of ancient humans such as Ötzi the iceman helps researchers understand the genetic predisposition to cardiovascular disease.

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Abstract drawing of microbes.
Exploring Microbial Dark Matter
Kamal Nahas, PhD | Apr 19, 2024 | 4 min read
An open-source search engine helps scientists identify hundreds of microbial metabolites in a matter of seconds. 
Children running through a field.
Aimless Monocytes Underlie a Rare Lung Disease
Niki Spahich, PhD | Apr 18, 2024 | 4 min read
Children with a multifaceted lung disorder share a receptor deficiency, which has implications for monocyte migration into the lungs.
Conceptual illustration of personalized medicine with medical icons next to a human face.
The Largest Whole-genome Sequencing Study in Cancer 
Danielle Gerhard, PhD | Apr 17, 2024 | 7 min read
Comprehensive genome sequencing of 13,880 tumors revealed somatic and germline mutations that could influence patient treatment and prognosis.
Colorful 3D model of the cone-shaped HIV-1 capsid core on a black background.
HIV Engages in Mimicry to Enter the Nucleus
Danielle Gerhard, PhD | Apr 16, 2024 | 5 min read
To enter the nucleus, the HIV-1 virus acts like a transport receptor, which presents new targets for antiviral therapies.
Grey cloud of smoke on a black background.
After the Smoke Clears: Scars on the Immune System 
Danielle Gerhard, PhD | Apr 15, 2024 | 6 min read
Smoking leaves epigenetic marks on DNA long after cessation, with consequences for adaptive immunity.
Depiction of human DNA helix. 
An Epigenetic Strategy to Control Bad Cholesterol
Maggie Chen | Apr 12, 2024 | 3 min read
Modifying markers on DNA allows scientists to lower cholesterol levels in mice, even long-term.
A person’s hand reaching for wheat.
Close Encounters of Skin and Nerve Cells
Kamal Nahas, PhD | Apr 11, 2024 | 4 min read
Scientists exploring the skin-nerve cell connection have only scratched the surface. New research highlights just how intertwined the two cells are.
Fluorescence microscopy imaging of astrocytes in culture, stained red
Friends and Foes: Astrocytes as Disease Targets
Deanna MacNeil, PhD | Apr 10, 2024 | 3 min read
A new platform for screening astrocyte reactivity helps researchers uncover potential therapeutic interventions to treat neurodegenerative conditions.
Red and gray round cells floating on a red background. 
Low Intracellular Iron Levels May Keep Blood Stem Cells Young
Alejandra Manjarrez, PhD | Apr 8, 2024 | 3 min read
Removing excess iron from aging mouse blood-forming cells enhances their regenerative capacity.
Image of fibroblast cell with nuclei (yellow), mitochondria (red)<br >, and microfilaments (blue).
Complicated CAP Does It All
Rachael Moeller Gorman | Apr 5, 2024 | 5 min read
Researchers found that actin filaments can behave counter to decades-old actin dynamics dogma, changing how biologists think about cell movement.
Two drawn heads on a blue background with gears in their heads. A red spot on two gears is magnified over one head.
Biological Sex Influences Brain Protein Expression
Shelby Bradford, PhD | Apr 4, 2024 | 3 min read
Neurological disorders often have sex biases, and these differences could be due to altered protein expression in the brain.
Two sister cells are seen in the foreground, while individual cells are seen behind them on a blue background.
Sister Cells Reveal Cancer’s Fate
Aparna Nathan, PhD | Apr 3, 2024 | 4 min read
A new method traces treatment resistant cells and predicts drugs that can make them more susceptible to cancer therapy.
A whitish neutrophil with a red multi-lobed nucleus.
Cell Surface RNA Helps Neutrophils Get Around
Holly Barker, PhD | Apr 2, 2024 | 4 min read
A new study confirms reports of membrane-bound RNA molecules and points to their role in neutrophil migration.
3D rendered RNA strand
MEGA CRISPR: Engineering Better Immunotherapies with RNA Editing
Deanna MacNeil, PhD | Apr 1, 2024 | 3 min read
Multi-targeted Cas13 screens help researchers avoid permanent DNA cuts and evade T cell exhaustion.
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Enter Our 2024 Top 10 Innovations Contest
The Scientist | Apr 1, 2024 | 2 min read
Submit your new product for a chance at being selected for a coveted spot in The Scientist’s 2024 competition.
An image of cells with the center stained green and some cells stained magenta over a black background.
Growing Milk-Secreting Mammary Organoids
Sneha Khedkar | Mar 29, 2024 | 3 min read
Mammary organoids derived from mouse embryonic stem cells could offer clues into mammary gland developmental origins and help researchers study breast cancer.
Lenses of a fluorescent microscope illuminate a sample on a microscope slide.
A Colorful Approach to Tracking Cellular Cargo
Niki Spahich, PhD | Mar 29, 2024 | 4 min read
Through immunofluorescence microscopy, a rainbow of stains shows Amy Engevik where proteins go in health and disease states.
Flagellated rod-shaped bacteria live on intestinal tissue.
Clostridia to the Rescue
Shelby Bradford, PhD | Mar 27, 2024 | 3 min read
Some commensal bacteria help shore up intestinal walls in mice, which can prevent food allergies.
A single channel splits into two micro-channels.
A Beating Heart on a Chip
Aparna Nathan, PhD | Mar 26, 2024 | 4 min read
Researchers used organ chips to mimic conditions that help heart cells mature.
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