After the (draft) sequence
Now that the dust has settled after publication of the human genome sequence, Sydney Brenner assesses the first draft.
Apr 17, 2001
We now have the two reports on the human genome sequence, one, in
I will begin by saying something about the two approaches used. GC based their approach on sequencing ordered, large-insert bacterial artificial chromosome (BAC) libraries which had previously been shown to produce data with 99.99% accuracy and no gaps. It...