Researchers in the United Kingdom have reported the country's second case of variant Creutzfeldt-Jakob Disease (vCJD) thought to be associated with blood transfusion. The patient involved had a different prion protein genotype than all other cases so-far identified, suggesting more people than previously thought may be susceptible.
The case, reported in
All previous cases of vCJD, whatever the method of transmission, involved people homozygous for methionine (MM) at codon 129 of
Both the latter groups, 58% in total, have...