Accuracy in Recounts

It can take a pathologist, moving a micrometer across a slide under a microscope, days to measure 10 different layers in a skin tissue sample. It can also take days to count regrown or restenosed endothelial cells to gauge the effect of a drug on, say, ruptured coronary artery elastic lamina. And a second pathologist may get different results. But Mark Braughler of TissueInformatics, speaking at the Techvest Tissue Repair, Replacement, and Regeneration conference in New York on Nov. 9, said his computer system accomplishes the former task in seconds, the latter in hours. TissueInformatics is a 38-employee Pittsburgh company that uses robotics to capture digital images of tissues from slides at high resolution and fuse them into a complete tissue representation. It uses remote imaging to acquire images worldwide for a syndicated tissue bank. Its software quantifies the structural components of skin, cornea, blood vessels and...

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