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Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
Short-lived Molecules Support Long-term Memory 
Short-lived Molecules Support Long-term Memory 

A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.

A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.

News & Opinion

Colorful dots, representing small pieces of plastic, on a blue background
Nanoplastic Ingestion Causes Neurological Deficits
Shelby Bradford, PhD | May 31, 2023 | 3 min read
Small plastic particulates can induce inflammatory responses in the gut and brain, but removing them reverses this damage.
EKG readout
The Circadian Rhythm of the Heart Rate
Katherine Paulin, PhD | May 31, 2023 | 3 min read
The sympathetic nervous system influences gene expression in the heart to regulate the day-night cycle of resting heart rate.
Neurons (green) fire differently depending on whether the astrocytes (red) they are grown with are cultivated from people with or without fragile X.
Astrocytes Fuel Erratic Firing in Fragile X Neurons
Lauren Schenkman, Spectrum | May 30, 2023 | 3 min read
This new understanding could one day lead to targeted treatments. 
SARS-CoV-2 self-assembling virus-like nanoparticle with spike proteins protruding from the surface.
New Technology Improves SARS-CoV-2 mRNA Vaccine-Induced Immune Responses
Elina Kadriu | May 30, 2023 | 3 min read
mRNA-encoded self-assembling enveloped virus-like particles presenting SARS-CoV-2 spike protein enhance immunity and may provide better protection against viral variants. 
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Sivni | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Cancer cell
Interrogating the Complexities of the Tumor Microenvironment
Alison Halliday, PhD | May 19, 2023 | 5 min read
Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.
3D rendered illustration of a coronavirus with an overlaid network of lines and dots.
Connecting the Dots That Link Diabetes and Infection Severity
Deanna MacNeil, PhD | May 22, 2023 | 4 min read
Researchers shed light on the immunometabolism of respiratory infection, providing an avenue towards safer COVID-19 therapeutics for those affected by metabolic disorders.
Scientist pipetting at the bench in white coat and purple gloves
Chek-Mate for Gliomas
Aparna Nathan, PhD | May 22, 2023 | 3 min read
New research may make immunotherapy possible for hard-to-treat brain tumors.
Editing genome stock photo
Resolving Discrepancies in Mouse and Human Autoimmunity Studies
Niki Spahich, PhD | May 15, 2023 | 4 min read
By editing primary T cells with CRISPR, researchers begin to settle a long-standing debate about a common autoimmunity risk variant.
Elderly woman holding cell phone
A New Smartphone Application Improves Memory Recall in Older Adults
Mariella Bodemeier Loayza Careaga, PhD | May 8, 2023 | 3 min read
Neuroscientists developed and tested a promising mobile app that mitigates age-related memory decline.
Semi-circle of colorful cancer awareness ribbons
Electric Fields Disrupt Cancer Cell Division
Danielle Gerhard, PhD | May 4, 2023 | 5 min read
A novel, non-invasive treatment using electrical currents exploits physiological properties of dividing cancer cells to prolong survival and augment current therapies.
Medical illustration of a scientist replacing part of a DNA molecule with tweezers, representing genome editing.
On the Hunt for the Next Breakthrough in Motor Neuron Disease
Deanna MacNeil, PhD | May 9, 2023 | 3 min read
Researchers leave no stone unturned in the search for a spinal muscular atrophy treatment strategy that uses base editing.
Side and front view of a male human skull
Mechanical Force on the Skull May Aid Bone Regeneration
Alejandra Manjarrez, PhD | May 1, 2023 | 3 min read
By mechanically inducing the expansion of cranial sutures in young adult mice, researchers stimulated stem cell proliferation that is key to healing bone injuries.
Man in blue shirt holding a paper representation of the intestines
Gut Bacteria Contribute to Anorexia
Kamal Nahas, PhD | May 1, 2023 | 3 min read
Microbiomes transplanted from women with anorexia nervosa into mice enhanced symptoms of the eating disorder, such as rapid weight loss and reduced appetite.
One hand holding the other, depicting pain in the joints
A Bacterial Culprit for Rheumatoid Arthritis
Hannah Thomasy, PhD, Drug Discovery News | Apr 27, 2023 | 4 min read
Scientists identified a species of Subdoligranulum that may drive disease.
Cas9 enzyme
Molecular Glue ‘Shreds’ Cas9 and Enables a New Form of CRISPR Control
Ida Emilie Steinmark, PhD | Apr 26, 2023 | 3 min read
In a bid to address safety concerns about immune reactions during treatment with CRISPR-based therapeutics, a new technique speeds up how quickly the body destroys the DNA-cutting enzyme Cas9.
Image of methylated DNA
Stress Increases Biological Age, But Recovery Can Revert It
Alejandra Manjarrez, PhD | Apr 21, 2023 | 2 min read
A new study relying on DNA methylation clocks suggests that the biological age of mouse and human cells can fluctuate in response to stressful events.
Image shows photorhabdus virulence cassettes (green) binding to insect cells (blue) prior to injection of payload proteins.&nbsp;
Engineered Bacterial “Syringes” Can Deliver Drugs Into Human Cells
Rohini Subrahmanyam, PhD | Apr 20, 2023 | 4 min read
Researchers repurpose tiny bacterial injection systems to specifically inject a wide variety of proteins into human cells and living mice.
fMRI scan of two brains
New Brain Network Connecting Mind and Body Discovered
Natalia Mesa, PhD | Apr 19, 2023 | 4 min read
A new brain network responsible for complex movements may upend what we know about neural maps in primary motor areas
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