The machine can be run in doctor’s offices and other point-of-care settings to give rapid results.
In recent years, laboratories on the continent have ramped up genomic sequencing capabilities, offering in-country analyses rather than outsourcing the job.
Federal agencies, academic institutions, and industrial partners are joining forces to combat COVID-19 using artificial intelligence.
Many researchers have stopped breeding mice, reduced the size of colonies, and established contingency plans in case animal care staff get sick.
Graduate students and postdocs are left wondering about the implications for their academic careers.
Under emergency protocols, doctors can request to use survivors’ plasma to treat some critically ill COVID-19 patients.
Hospitals and commercial companies are testing thousands of patients for COVID-19 daily, but face reagent and supply shortages.
The small number of genetic differences between the original strain of the novel coronavirus from Wuhan and those currently circulating in the US population indicates that a vaccine may likely offer lasting immunity.
The symptoms suggest SARS-CoV-2 might infect neurons, raising questions about whether there could be effects on the brain that play a role in patients’ deaths, but the data are preliminary.
CATHERINE OFFORD, SOURCE DATA: ECDC
The drug has a long track record in medicine, having been used since the 1940s as an antimalarial and there are some early indications it could work against SARS-CoV-2 infections. Jeremy Rossman of the University says he would expect chloroquine to inhibit SARS-CoV-2 in the lab, based on what is known about its ability to raise endosomic pH. “But there’s often a huge gap between how it works in the lab cells and how it works in the body,” he says. Larger clinical trials will be necessary to determine how effective the drug is.
There are three ongoing COVID-19 clinical trials at locations across China and the United States for remdesivir, which is manufactured by pharmaceutical company Gilead. Doctors in the US have also treated patients with the drug under the Food and Drug Administration’s compassionate use policy, and—while it’s not clear that it was because of remdesivir treatment—at least one patient recovered. Remdesivir has shown promise disabling coronaviruses in the lab, too.
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Coronavirus experts are intensifying their own research programs in response to the outbreak, while handling an influx of manuscripts from other researchers that require peer review. “I’m getting probably ten to twenty review requests a week. Then I’ve been reviewing five to six per week. Before the outbreak, I was sticking to mostly four to six coronavirus papers per month.”
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Like many other respiratory conditions, COVID-19—the disease caused by SARS-CoV-2—can vary widely among patients. Scientists are trying to figure out why that is and also why the new coronavirus, like its cousins SARS and MERS, appears to be more deadly than other coronaviruses that regularly circulate among people each winter and typically cause cold symptoms.
Like any other models, the projections of how the outbreak will unfold, how many people will become infected, and how many will die, are only as reliable as the scientific information they rest on. And most modelers’ efforts so far have focused on improving these data, rather than making premature predictions.
As scores of academic meetings get upended due to COVID-19, researchers are turning to virtual replacements.
Rhesus macaques can be infected with SARS-CoV-2, leading primate center scientists to try to prevent outbreaks in their colonies, especially as experiments on coronavirus start.
A small study of macaques finds they don’t develop a coronavirus infection the second time they are exposed, supporting the idea of using plasma from recovered patients as a treatment for COVID-19.
We present an economic plan for a collective sharing of scientific knowledge on the pandemic.
Under lockdown in a hotel, members of a plant ecology course continue to work and study as they seek a way to return home.
With mounting feelings of isolation, research projects derailed, and financial futures cast into doubt, grad students are anxious in the midst of the COVID-19 outbreak.
Infected children may harbor SARS-CoV-2 while showing less-severe symptoms than adults. Their young immune systems, ACE2 receptor levels, and even exposure to other coronaviruses might play a role in their resilience.
Stephen Schwartz, known for his work on the vascular system, is the first person associated with the university to succumb to infection with SARS-CoV-2.
Here are the lessons we’ve learned so far about the keys to virtual science education—including what to do about lab classes.
The World Health Organization warns that a lack of data on how many people have the disease could undermine containment and mitigation efforts in many countries.
Labs are trying to figure out who will care for animals and organoids and some clinical trials are put on hold.
Under an area-wide “shelter in place” order, scientists at some of the world’s leading universities scramble to continue working while confined to their homes.
Scientists’ latest understanding of the facts, the suspicions, and the discounted rumors of SARS-CoV-2’s transmission from person to person
Find out which meetings have been canceled, postponed, or are going ahead as planned.
Current methods to detect infections of the novel coronavirus rely on identifying particular genetic sequences, but new assays are being developed to meet the growing demand for rapid answers.
Preliminary modeling studies provide a shortlist of potential coronavirus intermediate host species.
The first volunteer will receive a shot of the synthetic RNA vaccine today.
EcoHealth Alliance President Peter Daszak speaks with The Scientist about how pathogens like SARS-CoV-2 jump species, and how to head off the next pandemic.
Researchers look to messenger RNA encased in nanoparticles, DNA plasmids, molecular clamps, and other approaches as they rush to design a vaccine against the new coronavirus.
There is no evidence backing the idea that SARS-CoV-2 originated from US servicemembers visiting Wuhan.
Disease experts have largely focused on how we got to where we are now with coronavirus infections. Improved data collection and sharing can enhance projections of what’s to come.
A preprint indicates that coronavirus transmission from surfaces is possible, but does not provide evidence that this has occurred in the COVID-19 pandemic.
Manufacturing sites are ramping up production of reagents needed to isolate SARS-CoV-2’s genetic material—a key step in testing for the virus.
It takes a median of five days after infection to get sick, and patients shed the most coronavirus particles early in the illness, according to two new reports.
Dozens of schools across 11 states have announced emergency policies to help curb the spread of COVID-19.
Contact tracing and genetic testing reveal how SARS-CoV-2 circulated among individuals for weeks, especially in the US, before being detected.
The creativity of citizen scientists could help researchers design proteins that may be able to fight the SARS-CoV-2 virus.
The WHO chief calls for swift action as universities in multiple countries shut down and researchers report kids can become infected.
The pathogen appears to have come from wild animals, virologists say, and there are no signs of genetic manipulation in the SARS-CoV-2 genome.
Critics of the practice say the guidance is irresponsible and could give users a false sense of security.
More cases emerge across the country as the global death toll from COVID-19 surpasses 3,000.
Administration officials have given contradictory statements about how COVID-19 will affect the US, and it is not clear who is leading the infectious disease response effort, critics say.
Organizers have cancelled conferences, COVID-19 quarantines have prevented some scientists in China from visiting their labs, and travel restrictions have left researchers stranded.
Random mutations in the SARS-CoV-2 pathogen’s genome help researchers track the spread and transmission of COVID-19, the disease it causes.
An increase in confirmed infections, particularly in Italy, Iran, and South Korea, has led to heightened measures to prevent the spread of the virus SARS-CoV-2.
Nearly 100 academic journals, societies, institutes, and companies sign a commitment to make research and data on SARS-CoV-2 and COVID-19 freely available, at least for the duration of the outbreak.
Researchers find 380 amino acid substitutions between 2019-nCoV and severe acute respiratory syndrome (SARS)-related coronaviruses.
Liu Zhiming is the eighth frontline health-care worker to die from COVID-19, and hundreds more have been infected.
Under careful watch of the World Health Organization, doctors will test a range of COVID-19 therapies, including HIV and flu antivirals, blood plasma infusions, and traditional Chinese medicines.
The National Institute of Allergy and Infectious Diseases releases a series of images that offer a close up look at the novel coronavirus SARS-CoV-2.
Scientists can provide essential information to educate the public about the coronavirus.
Some US states are waiting for the CDC to send replacement enzymes necessary for carrying out SARS-CoV-2 assays.
Authorities had silenced Li Wenliang after he spoke out about the virus, now known as SARS-CoV-2 in the early days of the epidemic.
The US Food and Drug Administration authorizes the distribution of the SARS-CoV-2 diagnostic to state health departments and other facilities.
Claims that a woman spread the virus to a colleague in Germany before she had symptoms conflict with health officials’ interview with the patient herself.
What is a publication to do when readers misuse its content?
Researchers are trying to figure out where it came from, whether it’s evolving, and just how big a threat it will be.