Menu

First Blood Test for Concussion Approved by FDA

The diagnostic measures two proteins indicative of brain injury.

Feb 16, 2018
Kerry Grens

WIKIMEDIA, U.S. NAVY PHOTO BY PHOTOGRAPHER'S MATE 3RD CLASS JEREMY L. GRISHAMThis week (February 14), the US Food and Drug Administration (FDA) approved the first blood-based screening test for concussions. The diagnostic, which measures the abundance of the proteins UCH-L1 and GFAP, can help identify which patients should be sent for a CT scan to confirm any brain damage.

“This is going to change the testing paradigm for suspected cases of concussion,” Tara Rabin, a spokesperson for the FDA, tells The New York Times.

In the approval announcement, the FDA stated that the test accurately predicted the presence of “intracranial lesions” 97 percent of the time, and appropriately indicated that there were none 99 percent of the time. In doing so, the screen could avoid CT scans for one-third of people who have a possible mild traumatic brain injury.

“It doesn’t replace CT in all cases,” Jay Alberts, director of the Cleveland Clinic Concussion Center, tells NBC News. “The reason you do those scans is to rule out a clinically important brain injury, which would need surgery. . . . But in 99 percent of concussions you do not need a CT scan because they’re not clinically important, meaning there’s not an immediate need for surgery.”

The FDA says the test could be used for the general population, and will be especially helpful to the military.

See “Experimental Drug Relieves Blast-Related PTSD in a Rat Model of Traumatic Brain Injury

April 2019

Will Car T Cells Smash Tumors?

New trials take the therapy beyond the blood

Marketplace

Sponsored Product Updates

Application of TruBIOME™ to Increase Mouse Model Reproducibility
Application of TruBIOME™ to Increase Mouse Model Reproducibility
With this application note from Taconic, learn about the effects of the microbiome on reproducibility and predictability and how TruBIOME™ helps researchers generate custom microbiota mouse models!
Getting More Consistent Results by Knowing the Quality of Your Protein
Getting More Consistent Results by Knowing the Quality of Your Protein
Download this guide from NanoTemper to learn how to identify and evaluate the quality of your protein samples!
Myth Busting: The Best Way to Use Pure Water in the Lab
Myth Busting: The Best Way to Use Pure Water in the Lab
Download this white paper from ELGA LabWater to learn about the role of pure water in the laboratory and the advantages of in-house water purification!
Shimadzu's New Nexera UHPLC Series with AI and IoT Enhancements Sets Industry Standard for Intelligence, Efficiency and Design
Shimadzu's New Nexera UHPLC Series with AI and IoT Enhancements Sets Industry Standard for Intelligence, Efficiency and Design
Shimadzu Corporation announces the release of the Nexera Ultra High-Performance Liquid Chromatograph series, incorporating artificial intelligence as Analytical Intelligence, allowing systems to detect and resolve issues automatically. The Nexera series makes lab management simple by integrating IoT and device networking, enabling users to easily review instrument status, optimize resource allocation, and achieve higher throughput.