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Mammalian Cloning Milestone: Mice from Mice from Mice

It was fitting, perhaps, that Cumulina the cloned mouse made her debut at a press conference in New York City on Gregor Mendel's birthday, July 22. As the father of genetics, Mendel explained genetic variability. As the first mouse cloned from an adult's cell nucleus, Cumulina represents the ultimate in genetic uniformity. So far, 50 mice have been cloned, some through three generations. Photo: ProBio America Inc. THREE GENERATIONS: Researchers at the University of Hawaii cloned these three g

Ricki Lewis

It was fitting, perhaps, that Cumulina the cloned mouse made her debut at a press conference in New York City on Gregor Mendel's birthday, July 22. As the father of genetics, Mendel explained genetic variability. As the first mouse cloned from an adult's cell nucleus, Cumulina represents the ultimate in genetic uniformity. So far, 50 mice have been cloned, some through three generations.

Photo: ProBio America Inc.
THREE GENERATIONS: Researchers at the University of Hawaii cloned these three generations of mice. At the top is the original nucleus donor. The middle and bottom levels show the second and third generations.
The cloning experiments began last summer in the laboratory of Ryuzo Yanagimachi, a professor of anatomy and reproductive biology at the John A. Burns School of Medicine at the University of Hawaii. Postdoctoral research associate Teruhiko Wakayama led the project, and other team members were postdoctoral researchers Anthony Perry...

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