Public-Private Genome Debate Resurfaces

Smoldering differences between the Celera Genomics Group and the Human Genome Project erupted last month as three leaders of the international public consortium published an online article in the Proceedings of the National Academy of Sciences (PNAS)1 criticizing the results published last year by Celera.2 For the first time in scientific literature, Robert Waterston of Washington University, Eric Lander of the Whitehead Institute for Biomedical Research's Center for Genome Research, and John Su

Brendan Maher
Apr 1, 2002
Smoldering differences between the Celera Genomics Group and the Human Genome Project erupted last month as three leaders of the international public consortium published an online article in the Proceedings of the National Academy of Sciences (PNAS)1 criticizing the results published last year by Celera.2 For the first time in scientific literature, Robert Waterston of Washington University, Eric Lander of the Whitehead Institute for Biomedical Research's Center for Genome Research, and John Sulston of the Sanger Institute published a long-held point of contention.3 They gripe that because scientists at Celera included DNA sequence information from GenBank, the public sequence repository, they neither published a true independent sequence of the human genome, nor provided a meaningful test of the whole genome shotgun method, currently being employed—at least in part—in the public effort to sequence the mouse. Some observers call the recent spat perplexing and speculate that...

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