Notebook
Reprinted with permission from Nature CKI produces complete secondary dorsal axes. Synthetic mRNA encoding CKI, mutant CKI (K > R), or Xwnt-8 was injected at the eight-cell stage into one ventral vegetal blastomere. Embryos injected with CKI or Xwnt-8, but not inactive CKI (K > R), developed complete secondary dorsal axes. CANCER CLUE The rush of discoveries over the past two years concerning the Wnt signaling pathway--known to be crucial to normal development and altered in human melano
Oct 10, 1999
Reprinted with permission from Nature |
![]() CKI produces complete secondary dorsal axes. Synthetic mRNA encoding CKI, mutant CKI (K > R), or Xwnt-8 was injected at the eight-cell stage into one ventral vegetal blastomere. Embryos injected with CKI or Xwnt-8, but not inactive CKI (K > R), developed complete secondary dorsal axes. |
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