The residents of California's San Diego County have voted by a 2-to-1 margin to continue to allow unclaimed pound animals to be used in medical research. More than 600,000 voters cast ballots November 6 in the largest-ever electoral rebuff of the animal rights movement's efforts to curb the use of pound animals in research. Supporters spent $130,000 to campaign for the referendum, which was drafted by county legislators and endorsed by such well-known scientific figures as former U.S. Surgeon General C. Everett Koop and Nobel laureate George Palade. There have been six such referenda--four in California--on the issue since 1986, says Barbara Rich of the Washington, D.C.-based National Association for Biomedical Research, and all have passed by similarly large margins.