Opinion: Test Brain-Reviving Technology in Infants First

If a system tested in decapitated pigs ever gets to human clinical trials, neuroscientific and ethical reasons point to testing babies before adults.

| 3 min read
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A recent Nature paper describing an artificial blood perfusion used in an attempt to restore brain function after pigs were decapitated has generated great discussions in the medical, scientific, and bioethical academic arenas. Although the study’s results showed marked improvement and restoration in many cellular and molecular functions within the brain, the artificial blood perfusion system, called BrainEx, failed to restore global brain activity associated with awareness, perception, or other higher-order brain functions whose absence are intrinsic to defining death.

Before such a system were to be applied to, say, revive brain activity in stroke patients, there are three scientific questions that remain to be addressed from the researchers’ study. First is whether their failure to restore global brain activity was due to the fact that the researchers waited up to four hours after decapitation before hooking up their system to the decapitated pigs. In ...

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Meet the Author

  • John Loike

    John D. Loike

    John Loike serves as the interim director of bioethics at New York Medical College and as a professor of biology at Touro University. His biomedical research focuses on how human white blood cells combat infections and cancer.
  • Alan Kadish

    Alan Kadish

    Alan Kadish is president of the Touro University System, the largest Jewish-sponsored educational institution in the United States. Before becoming Touro’s second president in March 2010, Kadish distinguished himself as a cardiologist, teacher, researcher, and administrator.
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