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CellarisBio

CellarisBio is a cellular biophysics company pioneering MICRO-TAG® cellular target engagement technology for next-generation drug discovery. MICRO-TAG® transforms drug discovery by enabling quantitative, real-time measurement of complex drug-target interactions directly in cells. Backed by multiple patents, CellarisBio is focused on unlocking challenging target classes, including membrane proteins, transcription factors, protein complexes and other intrinsically disordered proteins, many of which were previously considered “undruggable.” The MICRO-TAG® platform enables high-resolution cellular target engagement analysis across temperature-series workflows, providing mechanistic insights beyond conventional endpoint assays. Applications of MICRO-TAG® include hit discovery and validation, Cellular DEL discovery and functional mechanism-of-action studies, spanning multiple therapeutic modalities and target families. CellarisBio has also recently released a panel of MICRO-TAG® research reagents designed to provide streamlined access to real-time cellular target engagement workflows for research labs.

Content by CellarisBio

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Enhancing the Physiological Relevance of Drug Discovery

The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

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Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

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Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad
Beyond the Basics: Strategies for Single-Cell and Spatial Transcriptomics Analysis

Beyond the Basics: Strategies for Single-Cell and Spatial Transcriptomics Analysis

bioxcell
Scientist reviewing cellular and molecular data on a computer in a laboratory.

Building Translation-Ready Biomarkers with Connected Workflows

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Products

Closeup image of a multi channel pipette dispensing pink liquid into a 96-well plate.

The ASSIST PLUS pipetting robot for affordable workflow automation

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Single cells in suspension

Rapidly isolate primary cells and make uniform single-cell suspensions with Corning® Cell Strainers

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Abstract image representing cell membranes linked together.

CellBrite® Steady Membrane Stain: Cell surface staining built for real-time imaging

Biotium
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Monod Bio Licenses AI-designed Protein Technologies to SignalChem Biotech for Custom Discovery Assays