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In the 1950s, scientists began to suspect that single-ion channels existed, but it took them another quarter century to verify it.

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Journalist and author Fran Hawthorne has covered health care and business for more than 20 years for the New York Times, Fortune, Worth and Newsday among others. She is also the author of four books, including Inside the FDA, and most recently, Pension Dumping, published in April. In Diverting a Diet Drug, Hawthorne explores how a pharmaceutical company transitioned a weight-loss drug from being prescription-on

Animal research war wages I understand the frustration behind Conn's writing. 1 I can easily believe that the demonstrations in connection with his job interview swayed the board to pick another candidate for the job. On the other hand, I still believe that a great majority in the country realizes that there is no replacement for animal

Credit: Photo by Mick Hales" /> Credit: Photo by Mick Hales EYEING EVOLUTION » In Before Darwin, Eric Smith describes how Darwin's theories don't quite work for the early earth. For a closer look at the world on which Darwin based his ideas, this is your last chance to visit the New York Botanical Garden's exhibit Darwin's Garden, featuring the plants that inspired him. It closes June 15. For more, see http:

The Scientist Readers' Survey Methodology Best Places to Work in Industry 2008Survey Form: A web-based survey was posted on The Scientist web site from January 15 to March 7, 2008. Results were collected and collated automatically.Click here for survey questionsInvitations: E-mail invitations were sent to readers of The Scientist and registrants on The Scientist web site who identified themselves as working in commercial or industrial companies. Responses: 1929 useable an

Survey closes on June 6 - in September we'll publish the most current salary data and analysis for life scientists

The replication stutter During replication, DNA polymerases are positioned on each strand of DNA . Using a microscope slide as an anchor, we tethered DNA to a bead and stretched it with a flow of solution. We tracked how the position of the bead changed as the replication machinery went to work. Every time a lagging strand loop is formed in the DNA , the length of the strand is reduced (middle panel). Upon release of this loop, the DNA length suddenly increases, visible as an

Brian Stauffer is a Miami-based illustrator who blends photography, paintings and found objects to explore contemporary social issues. His work regularly appears on the covers and pages of The New York Times, Time, Rolling Stone, and New Scientist, among others. In 2005, his portrait of George W. Bush for The Nation was voted one of the top 40 magazine covers of the past

Translational disconnect I enjoyed the article by Alan Walton and Frederick Frank entitled "Translational disconnect," in which they discuss ways to approach the crisis in bioscience innovation. 1 I applaud the establishment of the Committee on Bioscience Innovations, of which I knew nothing until reading this article. I

WHY NOT WASHINGTON? » Any interest in running for office? If so, Scientists & Engineers for America is running a workshop May 10 to train scientists to run for office or work on an election campaign. To find out more about the "crash course" on being a political scientist, visit: https://tinyurl.com/2yc4nl. SEEING SCHNEYER » Alan Schneyer, the scientist we profile

Collision-activated dissociation (CAD), the most widely used peptide ion fragmentation technique for peptide sequence analysis by tandem mass spectrometry, works great for small peptides but is problematic for labile posttranslational modifications (PTMs). In the last decade, researchers have developed an alternative, electron capture dissociation (ECD), which involves reacting multiply-p

What do you do when you know your funding will soon run out?

Who's who in activism A sample of groups opposed to animal research, and how to tell them apart Related Articles The War on Animal Research Activists in the News UCLA sues animal rights groups Combating Malevolence Animal activists sentenced Oxford resumes building animal lab Name: People for the Ethical Treatment of Animals (PETA) Website: https://www.peta.org/ Key Features: Says it's the largest animal rights group worldwide

Kenneth Buetow is the director of the National Cancer Institute Center for Biomedical Informatics and Information Technology. He is also an intramural researcher at NCI, working on genomics. In 2004, Buetow and colleagues launched the cancer Biomedical Informatics Grid (caBIG) to help researchers manage and integrate the ever-growing dataset of clinical, genomic, imaging, pathological, and proteomic