© CSA-Images/istockphoto.com

In recent years, the bacterial communities living in and on our bodies have captivated scientists and the public alike. The gut microbiome has been tied to diverse functions and linked to both health and disease. But researchers now know that the gastrointestinal tract is just one of the many microbial homes on the human body. Even sites once considered sterile—such as the eye and the reproductive organs—are revealing themselves to be hotbeds of diversity. Here, The Scientist looks at some of these bacterial communities outside the gut, including the vagina, the penis, the breast, the lung, and more.

Recent Features

The Maternal Microbiome

Moms bombard their babies with bugs both before and after they’re born. By Kerry Grens


Characterizing the “Healthy” VaginaThe overly simplistic notion of a Lactobacillus-dominated vaginal microbiome is giving way to an appreciation of diverse and dynamic bacterial communities. By Jef Akst


Visualizing the Ocular MicrobiomeResearchers are beginning to study in depth the largely uncharted territory of the eye’s microbial composition. By


Parsing the Penis Microbiome

Circumcision and sexual activity are but two factors that can influence the bacterial communities that inhabit male genitalia. By Tracy Vence


Breathing Life into Lung Microbiome Research

Although it’s far less populated than the mouth community that helps feed it, researchers increasingly appreciate the role of the lung microbiome in respiratory health. By


Microbes of the Skin

Human skin, the barrier between the body and the outside world, is home to diverse microorganisms, some of which can promote immunity or fight invaders. By Jef Akst


Mining the Mouth’s Many Microbes

The oral cavity contains several distinct and dynamic microbial communities, and some of these commensals may seed the body’s other microbiomes. By Tracy Vence


From the August 2014 issue:

The Body’s Ecosystem

Research on the human microbiome is booming, and scientists have moved from simply taking stock of gut flora to understanding the influence of microbes throughout the body.

© ISTOCK.COM/LEONTURA/SORBETTO

Other microbiome news:

The Necrobiome

Mouth Microbe Turns Carcinogenic

Circumcision Alters the Penis Microbiome

Cystic Fibrosis Alters Microbiome?

Bacterial Sentinels of Noses

Microbiome Changes During Pregnancy

Microbial Menagerie

Opinion: Who Are We Really?

Q&A: Preserving The Body's Bugs

Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

Products

Eppendorf Logo

Research on rewiring neural circuit in fruit flies wins 2025 Eppendorf & Science Prize

Evident Logo

EVIDENT's New FLUOVIEW FV5000 Redefines the Boundaries of Confocal and Multiphoton Imaging

Evident Logo

EVIDENT Launches Sixth Annual Image of the Year Contest

10x Genomics Logo

10x Genomics Launches the Next Generation of Chromium Flex to Empower Scientists to Massively Scale Single Cell Research