Papers to Watch

S. Ge et al.,"A critical period for enhanced synaptic plasticity in newly generated neurons of the adult brain," Neuron, 54:559-66, May 24, 2007. "By following GFP-labeled newly-born adult dentate granule cells, a critical period of 1-1.5 months was identified, and the increased plasticity depended on developmentally regulated synaptic expression of NR2B-containing NMDA [N-methyl d-aspartate] receptors. This critical period may be important for mediating e

The Scientist Staff
Sep 1, 2007

S. Ge et al.,"A critical period for enhanced synaptic plasticity in newly generated neurons of the adult brain," Neuron, 54:559-66, May 24, 2007.

"By following GFP-labeled newly-born adult dentate granule cells, a critical period of 1-1.5 months was identified, and the increased plasticity depended on developmentally regulated synaptic expression of NR2B-containing NMDA [N-methyl d-aspartate] receptors. This critical period may be important for mediating experience-induced plasticity and stabilizing mature circuitry."

--Y. Peng Loh
National Institutes of Health, United States

B. Mitchell et al., "A positive feedback mechanism governs the polarity and motion of motile cilia," Nature, 447:97-101, May 3, 2007.

"The authors provide evidence for a two-step process by which motile cilia become oriented within the epithelium: The first step of rough alignment depends on developmental cues, while the second step depends on flow-mediated feedback from the cilia themselves."

--Jeffrey Axelrod
Stanford University, United States

L. Banaszynski et al.,...

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