A single gene drives endocrine pancreatic development
pancreatic islet cells.
Feb 14, 2001
By targeting a variety of pancreatic transcription factors to a region of the chick endoderm that is not normally fated for pancreas development, a team from the Department of Molecular and Cellular Biology at Harvard University, led by Doug Melton, has made some surprising discoveries.
The gene
The authors found that another transcription factor, encoded by
One of the approaches...