abo
Mutation of the Drosphila gene abnormal oocyte (abo), causes a recessive maternal-effect lethality, which can be rescued by specific regions of heterochromatin. In the October 9 Proceedings of the National Academy of Sciences, Maria Berloco and colleagues report a characterization of the abo protein product and its function (Proc Natl Acad Sci USA 2001, 98:12126-12131).Berloco et al. cloned the abo gene and showed that it encodes a chromosomal protein that binds specifically to the regulatory re
Oct 16, 2001
Mutation of the
Berloco
The authors conclude that Abo is a negative regulator of histone...