Actin checkpoint
Mitotic segregation of chromosomes depends on correct assembly of the bipolar spindle and mitosis is delayed by the spindle assembly checkpoint (SAC). In the July 19 Nature, Gachet et al., at the National Institute for Medical Research and University College London, describe a different mitotic checkpoint in yeast (Nature 2001, 412:352-355). They investigated the link between organization of the actin cytoskeleton and the cell cycle in the fission yeast Schizosaccharomyces pombe. They synchroniz
Jul 18, 2001
Mitotic segregation of chromosomes depends on correct assembly of the bipolar spindle and mitosis is delayed by the spindle assembly checkpoint (SAC). In the July 19