Adrenergic signalling affects progression of cardiomyopathy
-adrenergic receptor signalling or excitation-contraction coupling can prevent systolic dysfunction, exercise intolerance and cardiac remodelling.
Apr 18, 2001
In the course of chronic heart failure myocytes demonstrate changes in β-adrenergic receptor (βAR) signalling that impair cardiac contractility, but the role of these abnormalities in the progression of the disease is unknown. In 15 April
Freeman