Bacteriolytic therapy for cancer
Tumors often do not respond to chemotherapy because they contain large poorly vascularized areas that limit the efficacy of radiation and chemotherapeutic drugs. In November 27 Proceedings of the National Academy of Sciences early edition, Long Dang and colleagues from The Johns Hopkins School of Medicine show that administration of anaerobic bacteria in addition to chemotherapy can efficiently destroy large tumors.Dang et al. created a strain of anaerobic bacteria (Clostridium novyi-NT) lacking
Nov 29, 2001
Tumors often do not respond to chemotherapy because they contain large poorly vascularized areas that limit the efficacy of radiation and chemotherapeutic drugs. In November 27
Dang
This strategy, called 'combination bacteriolytic therapy (COBALT)', has the potential to add a new dimension to the...